翻訳と辞書 Words near each other ・ 3,4,5-Tri-O-galloylquinic acid ・ 3,4,5-Trimethoxybenzaldehyde ・ 3,4,8-Trimethoxyphenanthrene-2,5-diol ・ 3,4-Dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+) ・ 3,4-Diaminopyridine ・ 3,4-Dichloroamphetamine ・ 3,4-dichloroaniline N-malonyltransferase ・ 3,4-Dichlorobicyclo(3.2.1)oct-2-ene ・ 3,4-Dichloromethylphenidate ・ 3,4-Dichlorphenylisocyanate ・ 3,4-dihydroxy-2-butanone-4-phosphate synthase ・ 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase ・ 3,4-Dihydroxymandelic acid ・ 3,4-Dihydroxyphenylacetaldehyde ・ 3,4-dihydroxyphenylacetate 2,3-dioxygenase ・ 3,4-Dihydroxyphenylacetic acid ・ 3,4-dihydroxyphenylalanine oxidative deaminase ・ 3,4-dihydroxyphenylalanine reductive deaminase ・ 3,4-dihydroxyphthalate decarboxylase ・ 3,4-Dihydroxystyrene ・ 3,4-Dimethoxycinnamic acid ・ 3,4-Dimethoxyphenethylamine ・ 3,4-Dimethoxystyrene ・ 3,4-Dimethylmethcathinone ・ 3,4-Divanillyltetrahydrofuran ・ 3,4-Epoxycyclohexanecarboxylate methyl ester ・ 3,4-Epoxycyclohexylmethyl-3’,4’-epoxycyclohexane carboxylate ・ 3,4-Ethylidenedioxyamphetamine ・ 3,4-Methylenedioxy-N-hydroxy-N-methylamphetamine ・ 3,4-Methylenedioxy-N-isopropylamphetamine Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク 3,4-Dihydroxyphenylacetic acid ： ウィキペディア英語版 3,4-Dihydroxyphenylacetic acid |Section2= |Section3= }} 3,4-Dihydroxyphenylacetic acid (DOPAC) is a metabolite of the neurotransmitter dopamine. Dopamine can be metabolized into one of three substances. One such substance is DOPAC. Another is 3-methoxytyramine (3-MT). Both of these substances are degraded to form homovanillic acid (HVA). Both degradations involve the enzymes monoamine oxidase (MAO) and catechol-O-methyl transferase (COMT), albeit in reverse order: MAO catalyzes dopamine to DOPAC, and COMT catalyzes DOPAC to HVA; whereas COMT catalyzes dopamine to 3-MT and MAO catalyzes 3-MT to HVA. The third metabolic end-product of dopamine is norepinephrine (noradrenaline). DOPAC can be oxidized by hydrogen peroxide, leading to the formation of toxic metabolites which destroy dopamine storage vesicles in the substantia nigra. This may contribute to the failure of levodopa treatment of Parkinson's disease. A MAO-B inhibitor such as selegiline or rasagiline can prevent this from happening. It can also be found in the bark of ''Eucalyptus globulus''. This product has been synthesized (52% yield) from 4-Hydroxyphenylacetic acid via aerobic biotransformation using whole cell cultures of ''Arthrobacter protophormiae''. == References == 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「3,4-Dihydroxyphenylacetic acid」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.